Living cells constantly convert energy to sustain their metabolism. For example, respiration, the flow of electrons from an energy source to an electron acceptor, is essential to biological energy conversion in all living systems. We are developing living materials dynamically changing their behaviors according to encased cellular behaviors using principles in supramolecular chemistry and dynamic covalent bond formation between polymeric species and cell surfaces. The ability to construct living materials dynamically interacting and responding to the cellular behaviors will open new possibilities in building smart cell-material interfaces.